This study demonstrates that utilizing lisinopril with a conversion rate of 3 mg of captopril to 1 mg of lisinopril was safe and effective for controlling hypertension in pediatric patients
Conversions from Captopril to Lisinopril at a Dosage Ratio of 5:1 Result in Comparable Control of Hypertension.
A synthesis was not conducted by the authors since lisinopril therapy was a weakly dominant strategy. The conversion from captopril (in
A captopril conversion rate of 3 mg captopril to 1 mg lisinopril was used. This study demonstrated that utilizing a conversion rate of 3 mg of captopril to 1 mg of lisinopril can be considered safe and effective for management of hypertension after cardiothoracic surgery in children less than 7 years of age.
Captopril and enalapril are approved for infants and children; however, lisinopril is only approved for 7 years of age. This study evaluated safety and efficacy of converting from captopril to lisinopril in patients utilizing a pre-defined conversion of 3 mg captopril to 1 mg lisinopril.
A synthesis was not conducted by the authors since lisinopril therapy was a weakly dominant strategy. The conversion from captopril (in
Angiotensin converting enzyme (ACE) inhibitors, such as lisinopril, enalapril, ramipril, benazepril, and captopril, block the conversion of
Angiotensin converting enzyme (ACE) inhibitors, such as lisinopril, enalapril, ramipril, benazepril, and captopril, block the conversion of
Most angiotensin converting enzyme inhibitors are prodrugs, requiring hepatic conversion to an active metabolite. Captopril and lisinopril
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