The mechanism of action is unknown but amiodarone may Warfarin and other anticoagulant agents: amiodarone raises the concentration of warfarin.
Amiodarone markedly increases effect of warfarin sodium. Amiodarone inhibits cytochrome P450 mediated metabolism of warfarin.
Lu, Characteristics of the amiodarone‐warfarin interaction during long‐term Sanoski, Clinical observations with the amiodarone/warfarin interaction
Amiodarone can markedly increase the effect of warfarin sodium. Amiodarone inhibits cytochrome P450 mediated metabolism of warfarin.
Warfarin: Amiodarone increases the blood thinning effect of Warfarin. Warfarin: the INR will decrease upon stopping amiodarone. In most
Warfarin Drug Interactions Amiodarone 400 mg/day: Reduce Warfarin dose 40% Amiodarone 300 mg/day: Reduce Warfarin dose 35% Amiodarone 200 mg/
Warfarin Amiodarone Coadministration of Warfarin and Amiodarone increases the prothrombin time by 100%. Warfarin Enoxaparin If
Amiodarone has a significant drug interaction with warfarin. The anticoagulant effect of warfarin is potentiated with the addition of amiodarone
Warfarin Drug Interactions Amiodarone 400 mg/day: Reduce Warfarin dose 40% Amiodarone 300 mg/day: Reduce Warfarin dose 35% Amiodarone 200 mg/
Comments
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