Alpha-agonists used therapeutically are relatively selective or non-selective for 1 or 2-adrenoceptors. Besides the drugs listed below, there are sympathomimetic drugs that have -agonist and -adrenoceptor agonist properties. These drugs include the naturally occurring catecholamines, dopamine, epinephrine and norepinephrine.
Included in the list of sympathomimetic drugs are beta-adrenoceptor agonists and alpha-adrenoceptor agonists. Some sympathomimetics stimulate the release of
Alpha-nists, dexamethasone, midazolam, and nonsteroidal anti-inflammatory drugs are efficacious adjuvant drugs that require additional research on their safety (1014). 2 2. Alpha-2 Adrenergic Agonists (A2AA) 2.1. Clonidine Clonidine is a commonly used alpha-2-adrenergic agonist in regional anesthesia (14).
Similar to alpha-blockers, these drugs lower blood pressure by preventing the release of norepinephrine. Methyldopa is an alpha-2 receptor agonist. Alpha-2 receptor agonists can cause:
Alpha-nists or alpha-2 adrenoceptor agonists are drugs used to treat high blood pressure. Centrally acting alpha-nists stimulate alpha
(Tenex, Intuniv), an alpha-2 adrenergic agonist, and clonidine (Kapvay), a centrally acting alpha agonist. These medications are not
Centrally acting sympathoplegic Drugs Drugs Alpha-2 receptor agonists: clonidine Indirect acting adrenergic drugs: methyldopa Mechanisms of antihypertensive action a) Alpha-2 receptor agonists: Activation of alpha-2 receptors in Nucleus TractusSolitariusand in rostral ventrolateral medulla (the main mechanism). Activation of
Adrenergic Agonists ; Tizanidine, An alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity. ; Methoxamine, An alpha adrenergic agonist
Similar to alpha-blockers, these drugs lower blood pressure by preventing the release of norepinephrine. Methyldopa is an alpha-2 receptor agonist. Alpha-2 receptor agonists can cause :
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