Abuse of gabapentinoids

☑️@abuse_of_gabapentino · 2467 subscribers · Content 18+ 🔞
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Actual: Background: Gabapentinoid (pregabalin and gabapentin) abuse is increasingly being reported. Objective: To assess the extent of gabapentinoid abuse, characteristics of typical abusers, patterns of abuse, and potential harms in order to bring this trend to providers' attention.
4.5 rating 2025-04-24
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The abuse of gabapentinoids (i.e, pregabalin and gabapentin [GBP]), in particular, has been growing, and in 2024, gabapentinoids were one of the most commonly abused prescription medications

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Background: A 2024 systematic review (SR) identified 59 studies examining gabapentinoid (pregabalin and gabapentin) misuse/abuse. Evidence of gabapentinoid misuse/abuse has since grown substantially. Objective: Update previous SR and describe new insights regarding gabapentinoid abuse.

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In a proportion of the people abusing one of the gabapentinoids, it was used to potentiate the effect of methadone. The finding of gabapentinoid

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Background/aims: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone.

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Results: 22% (29/129) of respondents admitted to abusing gabapentinoids, and of these, 38% (11/29) abused gabapentinoids in order to potentiate

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Background/aims: There is emerging evidence of gabapentin and pregabalin (gabapentinoid) abuse, particularly in the substance misuse population, and some suggestion of gabapentinoids being abused alongside methadone.

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This article reviews the latest evidence of gabapentinoid (gabapentin and pregabalin) misuse/abuse, including risk factors, effects, and harms. It found that gabapentinoids are increasingly abused or misused to self-medicate or achieve euphoria, and that opioid use disorder is the greatest risk factor for gabapentinoid abuse.

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gabapentin and pregabalin (gabapentinoid) abuse methadone] found no information describing combined gabapentinoid and methadone abuse.

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Background: A 2024 systematic review (SR) identified 59 studies examining gabapentinoid (pregabalin and gabapentin) misuse/abuse. Evidence of gabapentinoid misuse/abuse has since grown substantially. Objective: Update previous SR and describe new insights regarding gabapentinoid abuse.

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