These bioactive compounds serve as the foundation for many modern pharmaceuticals. One of the essential polyphenols in various medicinal plants is Chlorogenic acid (CA), an ester of caffeic and quinic acid. Extensive research has revealed that CA possesses anti-inflammatory, anticarcinogenic, and antioxidant properties.
Coffee may reduce iron absorption, [5] possibly due to the presence of chlorogenic acid, a known iron chelator. [6] This mechanism can be extended to green coffee extract, which is an even richer source of chlorogenic acid. Tea, whether green [7] or black, [5] might inhibit iron absorption, possibly due to the presence of catechins [7] and
A seminal study posited that chlorogenic acid mitigated acetaminophen (APAP)-induced inflammatory perturbations in liver tissues, a modulation attributable to Nrf2 activation; intriguingly, this anti-inflammatory efficacy of chlorogenic acid was notably compromised in the absence of Nrf2 (Hu et al, 2024).
Chlorogenic acid is a component of common foods and beverages; coffee contains an average of 53.8 mg chlorogenic acid per 100 ml. [36] Therefore, to consume the level of chlorogenic acid used in the study, a human on a standard calorie daily diet (416 g/d; 250g carbs, 100g protein, 66g fat) would need to consume roughly 55 mL of coffee
Chlorogenic acid (CGA), otherwise known as 3-caffeoylquinate (3-CQA) or chlorogenate is a biologically active polyphenolic compound that represents an entire ester-hydroxycinnamic and quinic acid group involving dicaffeoyl, caffeoyl, coumaroylquinic and feruloyl acids respectively [44].
Objectives and design Chlorogenic acid, which belongs to the polyphenols, is an anti-oxidant and anti-obesity agent. In this study, we investigated the role of chlorogenic acid in inflammation. Materials and methods Anti-inflammatory effects of chlorogenic acid were examined in lipopolysaccharide (LPS)-stimulated murine RAW 264.7 macrophages and BV2 microglial cells. We observed the level of
by D Andrews 2024 Cited by 34bitter-blocking taste-modifiers but the list also included Taste-Masking Effect of Chlorogenic Acid (CGA) on Bitter Drugs Evaluated by Taste.
by Z Liu 2024 Cited by 89The experiments in vitro, in vivo have validated the anti-influenza effect of quercetin and chlorogenic acid, which indicating comparable
chlorogenic acid, limonene, and quercetin For these reasons, breastfeeding women should consult their healthcare provider before using fennel to stimulate
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Thanks for sharing, Tess (uk)
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