Among people with Type 2 diabetes recommended for first-line SGLT2i treatment, only 11.9% received a prescription for an SGLT2i, and there was no significant difference in prescription between people who met the criteria for first-line SGLT2i treatment versus people who did not meet the criteria for first-line SGLT2i treatment.
Recommendation for addition of an SGLT2i (or GLP-1RA where SGLT2i is not tolerated or contraindicated) to other glucose lowering medication(s) in adults
When Trulicity is added to existing metformin and/or pioglitazone therapy, the current dose of metformin and/or pioglitazone can be continued. SGLT2i When Trulicity is added to existing metformin and/or sodium-glucose co-transporter 2 inhibitor (SGLT2i) therapy, the current dose of metformin and/or SGLT2i can be continued.
Dulaglutide / Trulicity (GLP1-RA); Empagliflozin / Jardiance (SGLT2i); Liraglutide / Victoza (GLP1-RA) Empagliflozin / Jardiance (SGLT2i); Sitagliptin
If a patient is already on metformin and/or sodium-glucose co-transporter 2 inhibitor (SGLT2i) therapy, the current dose of metformin and/or SGLT2i can be
by GV de Cos 2024 Cited by 3Euglycemic DKA is a rare and dangerous adverse effect of SGLT2i type drugs. The use of SGLT2i is indicated only in type 2 diabetics; its use
Antihyperglycemic medication use was assessed on the drug class level including metformin, sulfonylureas, thiazolidinediones, SGLT2i
Antihyperglycemic medication use was assessed on the drug class level including metformin, sulfonylureas, thiazolidinediones, SGLT2i
SGLT2 inhibitors (SGLT2i) are new drugs for patients with heart failure (HF) irrespective of diabetes. However, the mechanisms of SGLT2i in HF remain elusive. This article discusses the current clinical evidence for using SGLT2i in different types of heart failure and provides an overview about the possible underlying mechanisms.
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