Levothyroxine and grapefruit juice

A clinically relevant interaction between grapefruit juice and levothyroxine appears unlikely.' Effects of grapefruit juice on the

Do not eat grapefruit or drink grapefruit juice while you are using levothyroxine. Dosing. The dose of levothyroxine will be different for different patients.

Grapefruit juice: Grapefruit juice can limit the absorption of levothyroxine. But the effect on actual thyroid levels is usually small. So, as long as

Grapefruit juice can decrease blood levels of levothyroxine, potentially decreasing the effectiveness of levothyroxine. Clinical research shows that grapefruit juice modestly decreases levothyroxine levels by 11% by inhibiting organic anion transporting polypeptide (OATP). Grapefruit juice is thought to affect OATP for only a short time.

Grapefruit juice may slightly delay the absorption of levothyroxine, but it seems to have only a minor effect on its bioavailability. Accordingly, the clinical relevance of the grapefruit juice-levothyroxine interaction is likely to be small. Introduction Grapefruit juice increases the plasma concentrations of

Coffee: Coffee can lower effectiveness and safety of levothyroxine by lowering its absorption. Grapefruit juice: Grapefruit juice can limit the absorption of

The effect of grapefruit on levothyroxine is the opposite: Drinking grapefruit juice or orange juice can inhibit uptake transporters and reduce the drug s absorption.

The effect of grapefruit on levothyroxine is the opposite: Drinking grapefruit juice or orange juice can inhibit uptake transporters and reduce the drug s absorption.

Grapefruit juice may, however, slightly reduce the body's ability to absorb the drug, so if you often drink grapefruit juice, levothyroxine