Pegfilgrastim vs filgrastim

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Actual: Pegfilgrastim, formed by the addition of a polyethylene glycol molecule to filgrastim, has comparable efficacy to filgrastim when administered only once per chemotherapy cycle. High-level evidence indicates that both filgrastim and pegfilgrastim improve the likelihood of completing dose-dense and dose-intense chemotherapy.
4.3 rating 2025-04-25
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However, as the authors highlight, there are also claims for superiority of pegfilgrastim over filgrastim, which has led to considerable debate over the equivalence of filgrastim and pegfilgrastim. Current clinical guidelines in both Europe and the US assume that filgrastim and pegfilgrastim are clinically equivalent [3, 4].

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Zarxio (filgrastim-sndz). Fulphila (pegfilgrastim-jmdb). Nyvepria among patients with nonmyeloid cancer receiving filgrastim vs a filgrastim biosimilar.

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Take medications filgrastim (Neupogen) tbo-filgrastim (Granix) pegfilgrastim (Neulasta) eflapegrastim (Rolvedon).

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by P Berto 2024pegfilgrastim versus daily filgrastim in patients receiving myelosuppressive chemotherapy. Comparison of pegfilgrastim with filgrastim on febrile

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Related drugs Filgrastim Lenograstim Lipegfilgrastim Pegfilgrastim.

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Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires less frequent dosing than filgrastim; however, pegfilgrastim has

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Hospital length of stay was longer in the tbo-filgrastim arm with a median of 20.73 days vs 19.61 days in the pegfilgrastim arm (P = .0032). Patients in the tbo-filgrastim group compared to the pegfilgrastim group had an increased incidence of neutropenic fever (76.7% vs 50.9%, P = .0034). Cost was assessed as well assessing average whole sale

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Prophylaxis with pegfilgrastim was significantly associated with lower FN-related chemotherapy disruption rates (8.3 vs 17.3% in the pegfilgrastim and filgrastim groups, respectively) and fewer FN-related days in hospital (0 vs 15 days, respectively).

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equivalent for both filgrastim- and pegfilgrastim-mobilized individuals (80% vs filgrastim (Granix), filgrastim (Neupogen) and pegfilgrastim (

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