Drugs that cause bone loss

Many drugs can affect bone metabolism. As examples, heparin, warfarin, cyclosporine, glucocorticoids, medroxyprogesterone acetate, cancer drugs, and thyroid hormone can cause bone loss, whereas thiazide diuretics can minimize bone loss [ 1,2 ].

Steroids can lead to bone loss, osteoporosis, and broken bones. When Inhaled steroids are less likely to cause bone loss than steroids taken by mouth.

Mood swings: Prednisone can cause mood swings, irritability, and even depression. Bone loss: Prednisone can cause bone loss and osteoporosis.

The drugs are supposed to strengthen bone and reduce fracture risk in people post-50. But for one leading cause of the bone-loss disease, a

Some chemotherapeutic agents are associated with excessive bone loss. High-dose methotrexate can directly cause bone loss [Schwartz and Leonidas, 2024]; whereas ifosfamide leads to bone loss secondary to renal tubular phosphate wasting [Pfeilschifter and Diel, 2024]. Other drugs, like cyclophosphamide, indirectly induce bone loss due to

Bisphosphonates are a class of drugs used to prevent loss of bone mass in conditions characterised by excessive bone resorption which causes bone fragility

Mood swings: Prednisone can cause mood swings, irritability, and even depression. Bone loss: Prednisone can cause bone loss and osteoporosis.

The drugs are supposed to strengthen bone and reduce fracture risk in people post-50. But for one leading cause of the bone-loss disease, a

doses for a long period of time, corticosteroid medicines can cause bone to be removed faster than it is formed. This causes loss of bone and therefore, bones