by J Cairns 2024 Cited by 26Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole Lower-dose vs high-dose oral estradiol therapy of hormone
Purpose The Letrozole (Femara) Versus Anastrozole Clinical Evaluation (FACE) study compared the efficacy and safety of adjuvant letrozole versus anastrozole in postmenopausal patients with hormone receptor (HR) positive and node-positive early breast cancer (eBC). Methods Postmenopausal women with HR-positive and node-positive eBC were randomly assigned to receive adjuvant therapy with
The Letrozole (Femara) Versus Anastrozole Clinical Evaluation (FACE) study compared the efficacy and safety of adjuvant letrozole versus anastrozole in postmenopausal patients with hormone receptor (HR) positive and node-positive early breast cancer (eBC).
Berndt, The long shadow of patent expiration. Generic entry and Rx-to-OTC De Placido, Adjuvant anastrozole versus exemestane versus letrozole, upfront or
The most common AEs in the letrozole versus anastrozole arms were arthralgia (48.2% vs 47.9%), hot flushes (32.5% vs 32.3%) and fatigue (16.8%
by R Homburg 2024 Cited by 501This raises the interesting question of whether letrozole or anastrozole could alleviate this situation and improve results. clomiphene citrate versus low-
by S De Placido 2024 Cited by 92Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA
The final analysis was done at 709 DFS events (letrozole, 341 [16.5%]; anastrozole, 368 [17.7%]). The 5-year estimated DFS rate was 84.9% for letrozole versus 82.9% for anastrozole arm (hazard ratio, 0.93; 95% CI, 0.80 to 1.07; P = .3150). Exploratory analysis showed similar DFS with letrozole and anastrozole in all evaluated subgroups.
anastrozole and letrozole: 0.63, 0.54), fracture episodes (OR vs. anastrozole Anastrozole (Arimidex) versus tamoxifen as first-line therapy in
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