Drugs discontinued before surgery

☑️@drugs_discontinued_b · 3908 subscribers · Content 18+ 🔞
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Actual: Temporarily discontinue PRADAXA before invasive or surgical procedures 2.8 Discontinuation for Surgery and Other Interventions. If possible, discontinue
4.4 rating 2025-04-27
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Garlic (discontinue at least 7 days before surgery) Gingko (discontinue at least 36 hours before surgery) Ginseng (discontinue at least 7 days before surgery) Kava (discontinue at least 24

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Garlic (discontinue at least 7 days before surgery) Gingko (discontinue at least 36 hours before surgery) Ginseng (discontinue at least 7 days before surgery) Kava (discontinue at least 24 hours before surgery) St. John's Wort (stop at least 5 days before surgery) Valerian (slowly taper off before surgery) Ang-Lee (2024) JAMA [PubMed]

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In the absence of either criteria, discontinue prior to surgery. Irreversible MAO antagonists may require 2 weeks after discontinuation of drug for normal MAO function to return. Therefore these medications should be tapered and discontinued two weeks before elective surgery.

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Semaglutide PO (Rybelsus) - 1 day before surgery. Liraglutide Discontinue 24hours before Surgery. Glucophage XR. Glumetza. Fortamet.

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Thus, Pradaxa needs to be discontinued earlier before surgeries, such as 2 or more days before surgery (see table). As to when to stop

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Discontinue rivaroxaban at least 24 hours before surgery. Discontinue at least 48 hr before elective surgery or invasive procedures with a moderate or high risk

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Garlic (discontinue at least 7 days before surgery) Gingko (discontinue at least 36 hours before surgery) Ginseng (discontinue at least 7 days before surgery) Kava (discontinue at least 24 hours before surgery) St. John's Wort (stop at least 5 days before surgery) Valerian (slowly taper off before surgery) Ang-Lee (2024) JAMA [PubMed]

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