Plavix and omeprazole

Omeprazole can reduce the effectiveness of Plavix, an antiplatelet drug, and increase the risk of cardiovascular events. Learn how omeprazole inhibits the liver enzyme CYP2C19 that transforms Plavix and what alternatives to consider.

Plavix (clopidogrel) patients should be Leading cardiologists challenge clinical importance of interaction between clopidogrel (Plavix) and omeprazole

omeprazole (Prilosec). If you're taking one of the drugs listed above Plavix and coffee (not an interaction). Plavix doesn't interact with coffee

The evidence for the interaction is so overwhelming, the FDA published labeling changes in the prescribing information for Plavix warning against taking it with omeprazole: Omeprazole, a moderate CYP2C19 inhibitor, reduces the pharmacological activity of Plavix.

(Plavix) and its use when As such, the FDA recommends. against the concomitant use of Plavix (clopidogrel) and omeprazole because the co-administration.

What is omeprazole? Omeprazole is a medicine that helps the blood thinners, such as warfarin (Coumadin and clopidogrel (Plavix))

The metabolism of clopidogrel can also be impaired by drugs that inhibit CYP2C19, such as omeprazole [Prilosec] or esomeprazole [Nexium]. Avoid concomitant use of Plavix with omeprazole or esomeprazole because both significantly reduce the antiplatelet activity of Plavix. Plavix Prescribing Information

omeprazole (Prilosec). If you're taking one of the drugs listed above Plavix and coffee (not an interaction). Plavix doesn't interact with coffee

Omeprazole can reduce the effectiveness of Plavix, an antiplatelet drug, and increase the risk of cardiovascular events. Learn how omeprazole inhibits the liver enzyme CYP2C19 that transforms Plavix and what alternatives to consider.