Bleeding. Risk increased when INR 3; Exponential increase when INR 5; Avoid giving NSAIDs, sulfas, macrolidies (azithromycin ok)
INR 1.8 1.9 No dosage adjustment may be necessary if the last two INRs were in range Repeat INR within 8 weeks Consider a one-time dose increase of 1 times daily maintenance dose If adjustment to maintenance dose needed, increase dose by 5-10% Repeat INR in 2 weeks INR 2.3 2.4 INR 2 3 Desired range
increase INR fluctuations. □ Lack of INR monitoring especially when prescribed with other drugs. Page 5. Prescription analysis-3 clinical
by D Leong 2024 Cited by 7steroidal anti-inflammatory drugs owing to increased bleeding risk, the INR of 0.17 per gram per day, with an average INR increase of.
Medications that interact with warfarin by increasing the INR and chances of a catastrophic bleed, or by decreasing the INR and exposing patients to the risk
Increasing the INR target or adding an antiplatelet drug should be considered if an embolic event occurs whilst the person is anticoagulated at the target INR.
Possible drug interactions with azithromycin include: Warfarin INRs may be increased in some people. Consider increased monitoring of INR. Any interaction appears to develop over the first 7 days. Digoxin azithromycin may increase the concentration of digoxin.
Medications that interact with warfarin by increasing the INR and chances of a catastrophic bleed, or by decreasing the INR and exposing patients to the risk
Clinical Impact: Increased INR and prothrombin time in patients receiving PPIs, including pantoprazole, and warfarin concomitantly. Increases in INR and
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