Drugs that cause methemoglobinemia

US FDA pregnancy category: X (for drug-induced methemoglobinemia); Not assigned (for acquired methemoglobinemia). Risk Summary: This drug can

with exposure to some oxidants drugs which require biochemical transformation before causing Methemoglobinemia.

by AS SCHWARTZ 2024 Cited by 28RECTOR, M.D. ST. LOUIS. Methemoglobinemia not caused by drugs or exogenous poisons is a relatively rare condition. A case of idiopathic methemoglobinemia.

Drugs and Toxins Known to Induce Methemoglobinemia. There are a lot of drugs that have been shown to induce methemoglobinemia. Some drugs are commonly used, while others not so much. Here s a table that I prepared for you that reviews some of the more common drugs and toxins known to cause methemoglobinemia:

Theoretically, nitrofurantoin can precipitate methemoglobinemia; other drugs causing methemoglobinemia, most commonly dapsone or benzocaine, in high-risk

Refer to UpToDate topics on methemoglobinemia for additional details regarding these medications and chemicals, as well as citations with supporting evidence for their role in causing methemoglobinemia. Genetic/heritable causes of methemoglobinemia include M hemoglobins and cytochrome b5-reductase deficiency (the latter is extremely rare).

Over-the-counter (OTC) benzocaine products can cause methemoglobinemia. Methemoglobinemia Please visit www.fda.gov/drugs/drug-safety

Drugs that can cause methemoglobinemia include: Prilocaine is metabolized by the liver to o-toluidine which oxidizes hemoglobin. Can cause dose-dependent (10mg/kg or 600mg) methemoglobinemia. 2,3; Benzocaine, a common ingredient in topical local anesthetic sprays, can also cause dangerous levels of methemoglobinemia in a dose-independent

by GC Kane 2024 Cited by 129cause methemoglobinemia. Estimates of methemoglobinemia drugs are rarely linked to the development of methemoglobinemia.