Dosage adjustment for IV Acyclovir in Neonate, Infant. Children and Adult Symptoms Signs: Over dosage of intravenous acyclovir has resulted in
Over all, acyclovir is a safe and effective drug with acyclovir-resistant HSV in an infant on long term suppressive acyclovir therapy.
acyclovir and over 200 infants exposed to valacyclovir during the first trimester of pregnancy. If you are applying acyclovir cream or
Valtrex During Pregnancy or Breastfeeding. The Acyclovir Registry documented outcomes of 1,246 infants and fetuses exposed to acyclovir during pregnancy (756 with
Gastrointestinal: Diarrhea (infants and children: 5%; adults: 1%), vomiting Valacyclovir is metabolized to acyclovir; data from the acyclovir
If the infant remains asymptomatic, a preemptive 10-day course of acyclovir should be completed. If at any time the infant becomes symptomatic, then treat as previously described with acyclovir for 14 to 21 days depending on type of disease.
Even with the highest maternal dosages, the dosage of acyclovir in milk is only about 1% of a typical infant dosage and would not be expected to cause any adverse effects in breastfed infants. Topical acyclovir applied to small areas of the mother's body away from the breast should pose no risk to the infant.
acyclovir to include dosing for infants with Neonatal Herpes Simplex Virus (HSV) based upon the infants post-menstrual age. Acyclovir (brand
The median daily dose of acyclovir was 60mg/kg (60, 66) with almost all infants receiving HD acyclovir therapy (79/89, 89%). Only 1 infant received 35 mg/kg/d. The remaining 9 infants (10%) received intermediate-dose acyclovir. At least one AE was diagnosed in nearly half of all infants exposed to acyclovir (40/89, 45%). Laboratory AEs occurred in
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