Trazodone 200 mg/day has no effect on sexual function in men with ED without major organic findings and non-compliance was an important issue in the present study. This study examined the efficacy of trazodone 200 mg/day in patients with erectile dysfunction (ED) without major organic findings.Patients and methods: Thirty-four patients with ED without
Subgroup analyses suggested that men with psychogenic ED might be more likely to benefit from trazodone than those with mixed or physiological ED. The efficacy of trazodone also appeared
Panel D: Isobologram for the combination of trazodone and gabapentin in the writhing test in mice. The ED 50 values are individually plotted for each drug on the axes and the straight line connecting trazodone and gabapentin ED 50 values is the theoretical additive line.
Subgroup analyses suggested that men with psychogenic ED might be more likely to benefit from trazodone than those with mixed or physiological ED. The efficacy of trazodone also appeared
In addition, taking into consideration the ratio between the trazodone and gabapentin ED 50 values (1.2:27.8), the fixed drug-dose ratio, based on mass quantity for trazodone and gabapentin, was established at 1:23.2.
Following ED 50 calculation, trazodone and gabapentin drug combination was administered in fixed-dose fractions of the calculated ED 50 (1/2, 1/
Background: Erectile dysfunction (ED) has been a prevalent disease worldwide. The mainstay of treatment for ED focused on oral medications extent of off-label use of trazodone for ED in
Erectile dysfunction (ED) is a worldwide problem. In Taiwan, the prevalence of ED is estimated to be 29% among men older than 40 years. 1 The treatment of ED was challenging prior to the development of phosphodiesterase-5 (PDE-5) inhibitors. Many drugs have reportedly been used to treat ED, including trazodone. 2 The use of trazodone to treat ED, especially for
Conclusions: The combination therapy of trazodone with sildenafil increased libido and sexual satisfaction on patients with ED. Therefore, combination of trazodone with sildenafil might be considered in ED patients of decreased libido with normal serum testosterone level rather than sildenafil monotherapy.
Comments
through life for a few months, then washing half a bottle of trazodone, or maybe oxycodone down with a bottle of gin, and just giving up. It really is sad.
5 stars