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Author: Admin | 2025-04-28
Such as visual inspection, thickness, diameter, hardness, friability, uniformity of the weight, and disintegration time test. From the study, it has been observed that all of the evaluated azithromycin tablets complied with the physical quality requirements.Visual inspection.Six different brands of azithromycin tablets were visually inspected for their consistency in terms of packaging, labeling, and physical characteristics of their tablets. The physical characteristics of the tablets evaluated in the study area revealed that they were free of breakage, cracking, and splitting. The tablets had a uniform shape, color, and markings. Additionally, all brands are free of embedded spots or contamination on their surface. Therefore, none of the tested brands’ packaging, labelling information, and physical attributes showed evidence of being spurious, faked, or fraudulent and agreed with the WHO visual inspection tool (S4 File).Thickness and diameter of test results.The thickness and diameter of all Azithromycin tablet brands tested were determined to be within their allowed limits (±5%) [31] (Table 4). The standard deviation of the thickness and diameter of tested products ranged from 5.3±0.02 to 6.9±0.03mm, and 16.7±0.09mm to 20.2±0.02mm respectively. As a result, all of the tested brands had thickness and diameter values that were deemed to be satisfactory as they were within the acceptable range. However, statistical analysis of the thickness and diameter results from a one-way ANOVA at a 95% confidence interval revealed a significant difference (pHardness test results.The hardness of azithromycin samples were investigated were in the range of 15.96±1.1Kpa to 27.5±0.6Kpa as reported (Table 4). Brand A5
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