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Author: Admin | 2025-04-28
General, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects 4. Bottom Line Amlodipine is a heart medication that may be used for the treatment of angina or to lower blood pressure but it can cause edema in the ankles or feet. 5. Tips May be taken with or without food.The manufacturer states that there is no concern about taking amlodipine with grapefruit juice. Be careful when going from sitting to standing as blood pressure may drop. Report to your doctor any signs of dizziness, tiredness, flushing, nausea, indigestion, shortness of breath, excessive weight gain, muscle rigidity or tremors, or edema. Dial 911 or report to an emergency department if wheezing, facial swelling, chest tightness, cough, or seizures occur suddenly.Do not stop taking amlodipine suddenly. Although no "rebound" effect has been reported, it is better to slowly decrease the dosage over some time.Your doctor may advise you to take sublingual nitroglycerin for any breakthrough angina pain. 6. Response and effectiveness Peak concentrations of amlodipine occur between 6 and 12 hours of an oral dose. The effect of amlodipine lasts for approximately 24 hours. 7. Interactions Medicines that interact with amlodipine may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with amlodipine. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Common medications that may interact with amlodipine include: anticonvulsants, such as carbamazepine or fosphenytoinantifungal agents, such as itraconazole or ketoconazolealfentanilamiodaronebeta-blockers, such as atenolol, labetalol, or metoprololbuspironebenzodiazepines such as midazolam or triazolamcarbamazepinecimetidinecyclosporinerifampinlovastatin or simvastatinquinidineNSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of amlodipinesildenafilother medications that inhibit or induce CYP 3A4.Note that this list is not all-inclusive and includes only common medications that may interact with amlodipine. You should refer to the prescribing information for amlodipine for a complete list of interactions. Further informationRemember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use amlodipine only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2025 Drugs.com. Revision date: October 3, 2023.Medical Disclaimer
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